SER

SERINE

Find entries where: SER

is present as a standalone ligand in 109 entries

as a non-polymer is covalently linked to polymer or other heterogen groups 51 entries

is present in a polymer sequence 220,798 entries

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Chemical Component Summary
Name	SERINE
Identifiers	(2S)-2-amino-3-hydroxy-propanoic acid
Formula	C₃ H₇ N O₃
Molecular Weight	105.093
Type	L-PEPTIDE LINKING
Isomeric SMILES	C([C@@H](C(=O)O)N)O
InChI	InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1
InChIKey	MTCFGRXMJLQNBG-REOHCLBHSA-N

Chemical Details
Formal Charge	0
Atom Count	14
Chiral Atom Count	1
Bond Count	13
Aromatic Bond Count	0

Drug Info: DrugBank

DrugBank ID	DB00133
Name	Serine
Groups	nutraceutical investigational
Description	A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from glycine or threonine. It is involved in the biosynthesis of purines; pyrimidines; and other amino acids.
Synonyms	beta-Hydroxyalanine Serinum (S)-2-Amino-3-hydroxypropanoic acid Ser alpha-Amino-beta-hydroxypropionic acid Serina L-Serine (S)-Serine Serine
Brand Names	Primene 10% Essepna Aminosyn II 7% With 50% Dextrose Aminosyn II 7% M In 10% Dextrose(dual Chamber) Aminosyn 7% 5% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose Aminosyn II and Dextrose Renamin (amino Acids) Injection Smofkabiven Electrolyte Free ProcalAmine Aminosyn II 7% With 10% Dextrose 2.5%travasol Amino Acid InJ.W.eleC.W.25%dex Aminosyn-PF Clinisol Primene 10%-liq IV FreAmine III Aminosyn 8.5% Kabiven Synthamin Clinimix 2.5% Travasol Aa Without Electrolytes In 10% Dextrose Injec Olimel 4.4% E 4.25%trav. Amino Acid InJ.W.O.elect.5%dext. Premasol - sulfite-free (Amino Acid) Periolimel 2.5% E Vamin 18 Electrolyte-free Aminosyn II 10% With Electrolytes Novamine 4.25% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose TrophAmine 4.25% Travasol Amino Acid Injection Without Electrlytes In 10% Dextrose Olimel 4.4% Aminosyn-PF 10% Aminosyn II with Electrolytes in Dextrose with Calcium Smofkabiven Peripheral Olimel 7.6% Clinimix E Aminosyn II 8.5% With 50% Dextrose Aminosyn II in Dextrose Perikabiven Hepatasol Aminosyn HF ProSol Travasol Aminosyn 5% Aminosyn II 7% Injection Plenamine Aminosyn II with Electrolytes Aminosyn 8.5% Injection With Electrolytes Olimel 5.7% E Smofkabiven Vamin N Nutrineal Pd4 4.25% Travasol Amino Acid Injection Without Electrolytes In 25% Dextrose 4.25% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose Aminosyn 3.5% M Primene HepatAmine Aminosyn II 8.5% M In 20% Dextrose (dual Chamber) Aminosyn Aminosyn II In Dextrose Injection 2.75% Travas. Amino Acid InJ.W.elecw.25%dex Smofkabiven Extra Nitrogen Electrolyte Free 4.25% Travasol Amino Acid Injection With Electrolytes In 25% Dextrose Aminosyn II RenAmin FreAmine HBC Olimel 7.6% E 2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose Aminosyn 10% W Electrolytes Olimel 5.7% Aminosyn II 5% Inj Clinimix 20% Prosol Aminosyn-PF 7% 5% Travasol Amino Acid Injection With Electrolytes In 20% Dextrose 4.25% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose Olimel 3.3% E Smofkabiven Extra Nitrogen 8.5% Freamine III Aminosyn II 8.5% Injection 5% Travasol Amino Acid Injection Without Electrolytes In 20% Dextrose Aminosyn Sulfite Free 2.75%travasol Amino Acid InJ.W.eleC.W.5%dex. 4.25%travasol Amino Acid InJ.W.elecw.5%dex.
Indication	Used as a natural moisturizing agent in some cosmetics and skin care products.
Categories	Amino Acids Amino Acids, Neutral Amino Acids, Peptides, and Proteins Dietary Supplements Proteinogenic Amino Acids Supplements
CAS number	56-45-1

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Cystathionine beta-synthase	MPSETPQAEVGPTGCPHRSGPHSAKGSLEKGSPEDKEAKEPLWIRPDAPS...	unknown
L-serine dehydratase/L-threonine deaminase	MMSGEPLHVKTPIRDSMALSKMAGTSVYLKMDSAQPSGSFKIRGIGHFCK...	unknown
Serine racemase	MCAQYCISFADVEKAHINIRDSIHLTPVLTSSILNQLTGRNLFFKCELFQ...	unknown
Serine palmitoyltransferase 2	MRPEPGGCCCRRTVRANGCVANGEVRNGYVRSSAAAAAAAAAGQIHHVTQ...	unknown
Serine palmitoyltransferase 1	MATATEQWVLVEMVQALYEAPAYHLILEGILILWIIRLLFSKTYKLQERS...	unknown
Serine--tRNA ligase, cytoplasmic	MVLDLDLFRVDKGGDPALIRETQEKRFKDPGLVDQLVKADSEWRRCRFRA...	unknown
Serine--pyruvate aminotransferase	MASHKLLVTPPKALLKPLSIPNQLLLGPGPSNLPPRIMAAGGLQMIGSMS...	unknown
Monocarboxylate transporter 10	MVLSQEEPDSARGTSEAQPLGPAPTGAAPPPGPGPSDSPEAAVEKVEVEL...	unknown	inhibitor
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Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource Name	Reference
PubChem	6857581, 5951
ChEMBL	CHEMBL11298
ChEBI	CHEBI:33384, CHEBI:17115
CCDC/CSD	ZIXBOA, AYACUZ, NELRAX, RIWKUD01, DLSERN34, YIGLUX, DLSERN12, XENXUL02, TIXGOW, MIFQUN05, MIFQUN04, MIFQUN06, EYOQOY, MIFQUN07, MIFQUN08, MIFQUN03, VOKHEJ, MIFQUN02, JEJVEA, MIFQUN10, MIFQUN, XATVUK, REZPET, AJODUA, MIFQUN09, JEJVAW, REZPAP, BUTBOJ, GUQBUR, AJODOU, KERMID, XENXUL01, XENXUL, TACPAS, PAZCUO01

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.

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SER

SERINE

Chemical Component Summary

Chemical Details

Drug Info: DrugBank

Drug Targets

Related Resource References