VIB

3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM

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is present as a standalone ligand in 18 entries

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Chemical Component Summary
Name	3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM
Synonyms	THIAMIN; VITAMIN B1
Identifiers	2-[3-[(4-amino-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
Formula	C₁₂ H₁₇ N₄ O S
Molecular Weight	265.355
Type	NON-POLYMER
Isomeric SMILES	Cc1c(sc[n+]1Cc2cnc(nc2N)C)CCO
InChI	InChI=1S/C12H17N4OS/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15)/q+1
InChIKey	JZRWCGZRTZMZEH-UHFFFAOYSA-N

Chemical Details
Formal Charge	1
Atom Count	35
Chiral Atom Count	0
Bond Count	36
Aromatic Bond Count	11

Drug Info: DrugBank

DrugBank ID	DB00152
Name	Thiamine
Groups	approved nutraceutical investigational vet_approved
Description	Thiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS. It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. Thiamine was first discovered by Umetaro Suzuki in Japan when researching how rice bran cured patients of Beriberi. Thiamine plays a key role in intracellular glucose metabolism and it is thought that thiamine inhibits the effect of glucose and insulin on arterial smooth muscle cell proliferation. Thiamine plays an important role in helping the body convert carbohydrates and fat into energy. It is essential for normal growth and development and helps to maintain proper functioning of the heart and the nervous and digestive systems. Thiamine cannot be stored in the body; however, once absorbed, the vitamin is concentrated in muscle tissue.
Synonyms	Thiamine chloride Thiamine Thiamin Thiaminum Vitamin B1 Tiamina Antiberiberi factor Thiamine hydrochloride thiaminium Thiamine mononitrate thiamine(1+) thiamine(1+) ion Aneurin
Brand Names	B1 Tab 100mg Orange Flavored Crystal Chews Tab PureVit DualFe Plus Multi Vitamines - Liq Childrens Chewable Multiple Vitamins Plus Fe Multivit-liq Nutrol-B-complex Vital-D Rx Zoo Chews Plus Iron Tini-cal Ampoules Mycelized Childrens Multi-vitamin Liq Triveen-Duo DHA Viva CT Prenatal Multi Vitamin-mineral Formula Cyroplex Iron Folate Plus Thiamine Hydrochloride Injection USP, 100mg/ml Fizz Multivitamins for Kids W C Loz PreferaOB Stress Ctr Srt Medi Msm (methyl Sulfonyl Methane) Dialyvite 5000 NataChew Multisol Vitafol-OB Plus DHA Prenatal Supplement Plus DHA Mvc 9+4 Inj WesTab Plus Low Potency B Complex Tab Mega Plex III - Pck Megavites Tab Maxum Multi-vite Stress Formula B-comp + 500mg Vit C Tab Thiamine HCL 100 mg Mvc 9 Plus 3 Inj Multi Vitamin Plus Iron Biovim Tab Biovita Daily Balance Tab Swiss One Timed Release Tab K.L. Vitamin-mineral Cavan Folate DHA Children's Chewable Multivitamin and Multimineral Maltlevol 12 Liq Multi Plex I - Tab Chewable Multiple Vitamins Plus Extra C Thiamine HCl Tab 100mg Geritol Liquid Kanga-V Multivitamins & Minerals Formula B Cavan Prenatal Permathene-12 - Caplet ahoSAN Multi-12/k1 Pediatric Lexazin Forty Plus Vitamin Supplement Vp-heme Ob Nutrilite Double X Usana Megavitamin Tablets - Tab Protect Plus SO 60 Vitaphil 90 DHA New Chapter's D'adamo 4 Your Type Multiple for Type O Se-Natal 19 Chewable Mega 13 Multivitamin Formula Complexe B-75 Children's Chewable Multi-vitamin Complete With Minerals Formula D.S. Stress Forte Plus Lipotropic Factors WesCaps Allbee With Vitamin C Cap NeuroBion Multinate DHA Children's Chewable Multivitamin Complete With Minerals Multiple Vitamins Plus Iron - Tab B Complex W C and B12 Inj Stresstabs + Zinc-copper Vigem 12 Liquid Vita-amine Cap 100mg Gtf-vitamin-minerals & Pancreatin Tab Multiple Vitamins and Minerals Stress Formula Tab Vitamin B1 100mg Vol-Care Rx Dia-vite RayaVit Vitachrom Gc Jenliva PNV Prenatal Plus Multivitamin Prenatvite Plus Ellis Tonic L-Methyl PNV DHA Multiple Vitamins Childrens Chewable Duet DHA Quflora Pediatric Drops Kaydia Patch Stress Formula Xyzbac Gestamine Comprimes Olympian Multi Vit Plus Minerals Tab G.A.S. Complex Se-Natal 19 Senior Multi One L.C. Supplement Oncovite Multi Enfants Tab Prenatryl Vitalife - Capsule Multra With Iron Vitamin B Cpd W Vit C Tab Tandem OB PreQue 10 Vitamin B1 Duet DHA 400 Edge OB Neomultivite Multi B Virt-Nate DHA Virt-PN Prena1 Plus Vitamine B1 100 Mg - Tablet Paire OB Plus DHA Formula O.C. Foltabs Prenatal Plus DHA HemeNatal OB plus DHA Vol-Plus Bugs Bunny and Friends Multiple Vitamins Allbee With C 550 Cap FolaGent DHA B Compound 50mg Tab Flinstones Multiple Plus Iron P.N.P. Vitamin Drink Super Vita-vim With Beta-carotene - Tab Folica-V Vita Balance 2000 Vitogen B Stress C600 Stress B & C Caplet Chela-manganese 50 Plus Children's Chew Multi & Min Tab Multiple Vitamins and Minerals Capsules M.V.I. Adult Vitamin B Complex Plus C 300mg Timed Release Complete Mega B Vitrexate FE Corvite Multivitamin & Minerals (iron Free) Omega-3 Rx Complete Balanced B-100 B-complex Vitamins Tab Phytovim Cap Supravite 10ml Ampoule Prenatal Plus Multivitamin Plus DHA MiniCaps Formula Gly Multi-vitamines Enfants Comprime Totalvit Plus Multivit Et Fer Ampoules Et Comprimes Prenate Star Prenatvite B Stress C + Iron & Vite Children Choice Multivitamin W Iron Chew Tab Premium Prenatal - Tablets Thiamine Hydrochloride Inj 100mg/ml USP TriStart DHA Escavite Folitin-Z Re Ob 90 DHA Multi Rol Multi-Vitamin Multiple Vitamins & Minerals Tablets Poly Vi Flor Chewable Tab Nephron FA Vc II One A Day Advance Adults 50+ tensioSAN Multi-force for Women Tab Prenatal Bal-Care DHA Prenatal and Post Partum Supplement Vege 1 Daily Tab Chewable Multivitamins Plus Iron Cavan Folate OB Fem Time Tab Neo Vites Tab B Complex Tablets M.V.I. Paediatric Innersource Tab Prenatal Vitamins Plus Low Iron Trinaz Virt-Nate Deriton Flintstones Multiple Vitamins Tab Childrens Multiple Vit and Min Chew Tab Potassium Plus Vit B Complex Swiss One Neo-bex Injectable Chewable Multiple Vitamins Tab B-complex 100 Infa Drops Multivitamins L.G.I.T. Lipo-B-C Tab Ribotin-E Trinatal GT Virt-Vite Plus Women's Change Formula B With C 500 Cap Chela Iron Plus C,b Complex Supravite C 1000 Palm Springs Multvit and Min Tab Z Bec Tab Everyday Multiple Vitamins Childrens Chewable Multiple Vitamins W.iron HemeNatal OB Garfield Chewable Multivits Plus Iron Tab RenaPlex Somarexin and C 1000 Multivitamines Pour Enfants (chewable Tablets) Mega Capsules Nephrocaps-QT hormaSAN forte PNV Tabs 29-1 Materna - Tab B Complex With C 300mg Tab Reaphirm Plant Source DHA Vitamine B1 Tab 100mg USP Women's Formula Dynam Ampoule Et Tablet Revit Tab Gtf Support Caplet Balanced B-complex Vit + Vit C&e Tab Lipovite Strovite Forte Caplet Ultimate OB DHA Hi Potency B52 B Complex Tab Vitamin B-1 Thiamine HCl 100mg Folica BE Vege Swiss One Multivitamin W Chel Mins Tab Vp-heme Ob DHA Pregvit Complexe B 75mg Advanced B & T Formula Hi Potency Stress B Tension With C Hylavite Stress Tablets Swiss Total One THIAMINE HYDROCHLORIDE injection, solution Luna Vitamin and Mineral Bar for Women Dialyvite 3000 Multi Vitamin and Fluoride Provida OB Venexa FE Multivitamines Et Mineraux Phytopure MVC-Fluoride Polymine Avec Zinc Et Cuivre Balanced B-50 Complex Chewable Multiple Vitamins for Children Materna-tab Premium Prenatal Concept DHA Liqui Vita Virt-Advance Super Charged Energy Super Multi Twin Ultra Liquid Grape Flavor Focalgin 90 DHA Kids Stuff With Iron Tablets Thiamine Hydrochloride Inj 100mg/ml B Complex 500 Tab Floravit - Syr Zavitrol Bal-Care DHA Essential Multivitamins and Minerals for Young Men Multivitamins W Minerals Extra Strength Twin G.F. Powder Vanilla Flavor Vitamin B Compound With Vitamin C Fortis Capsule Dtc Beminal With C Fortis Pws Select-OB Plus DHA Prenatal Supplement Plus DHA Iberet 500 Duet DHA Balanced Master Key Multi Vitamin Multi Mineral Formula 2 Vita B + C 500 Tab Natal-V RX Multi-vitamin/Multi-mineral Kids Stuff Tablets Multra Plex Soluvit N Liquid B Complex 50 Multitam VIL-Rx Dialyvite with Zinc Folet DHA Hylazinc Revitex Ampoules Et Comprimes Childrens Chewable Tab Pre-Tabs DHA Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA Vitafol Fe Plus Vitamin B Complex 100 Fortistress Tab Virt-Bal DHA Plus Complete-RF Prenatal Multivitamines Plus Fer Pour Enfants (chewable Tablets) Preplus RE Nata SetonET Multi Vitamin Drops with Fluoride Vitrexyl Multiple Vitamins With Minerals Tablets Choice OB DHA Mor-vites Tab Magnum-75 Vitamin and Mineral Supplement Paramettes Multivits Plus Iron Tab (teens) Multi II IV Vi Tab Vitaflex Dietary Suplement Xvite Floradix Formula Liq Tricare Prenatal DHA One B-plus - Tab Childrens Chewable Multiple Vitamins Multiple Vitamin Plus Minerals Tab Multivitamins W Iron Multiple Vitamins - Tablet Poly-Vite/Iron Oral Solution CitraNatal Assure Dermamed Nutrition for troubled skin Virt-Caps WesNatal DHA Complete Virt Vite GT TriAdvance MultiVitamin with Fluoride Stress Formula Multivitamin Tablets USP Vitamin B1 Tab 2mg USP Carbassist Tablets Multi-force for Adults Tab Flintstones Multiple Vitamins Plus Iron Neonatal Vitamin Children's Multivitamins Tricare Prenatal DHA One Rx Multivitamin Hi Potency Balanced B-100 Complex - Tab Children's Chewable Multi Vitamins With Iron Tablets Doctor's Choice Brand for Men One A Day Advance Fem C-B Complex Children's Chewable Tab Multicaps Prefera OB plus DHA Vitabanks Vitamin Tab INATAL Ultra PreGen DHA Multinate DHA Extra Sibergin B - Cap B-complex-50 Tab Multi #2 Stress Formula Vit B With C Complex Animal Shapes w/Iron Chewtabs Super Vitalex Ampoule Buvable Dayavite Cc II PR Natal 430 Swiss One Multi Vit & Chel Min Tab Vp-pnv-dha Super-pote Vitamin Supplement Vitasure Enrich Core Pack - Children Vitamin and Mineral Supplement VitaXyme Multi-Vit with Fluoride and Iron Multi-Vit-Flor Men's 50+ Orifer F Vitamin B Complex 100 Tab B50 B Complex Tab Gemvites Jr Tab Chewable Nitro Vites - Tab Renate DHA Dialyvite Supreme D Vita-Rx Diabetic Vitamin Animal Shapes Vitamin & Mineral Formula 1 Dietary Supplement Vitamin B-Complex Maximum Once A Day Multi Vitamin & Minerals Only One - Tablet Phosthenine Vitamines Et Fer (ampoules Buvable) Tonicol Et A-D-C Ampoules/comprimes Mega Vitaminerals Vasula Tab B-complex 50 Vitafol OB Caplet Dialyvite Vyqua Multi-12 Pediatric Chela-chromium 200 Maxi 10 Tab Super B Compound W 500mg Vit C Multipack II Balanced B-50 B-complex Vitamins Tab Kanga-kid Vitamins & Iron Children's Chewable Multivitamins and Minerals Prenara Timed Release B-complex 100 Stress Formula Multi-B Comp + 500mg Vit C Cap PreTAB B Complex With C 300mg Ultra Enerforce PreNatal Vitamins Plus Thiamine Hydrochloride B Complex 50+ Caplet Children's Chewable Multi-vitamin Complex-75 Daily Energy Brand B-complex Multivitamins and Minerals for Women Prenatal, DHA Stress B Complex With C,e, Zinc and Copper Vitamines Et Mineraux Enfants 970 Multi-vitamins With Minerals Puralor Spectrum 2 Cap Twin Ultra Liquid Orange Flavor Multi Pro Formula Gm Pregnancy Multivitamin Folic 5 B Complex 50 Vitamin Cap Folivane-Plus with Ascorbic Acid Precursors Vitamin B Tablets Inatal Advance Men's Isotonix Multitech Vitamin Mineral Supplemen B Complex W Vitamin C Fortis Cap Multi Vitamin with Fluoride Multi Vite Liq Adult Pregnancy Multivitamin Stressmates Ziphex Dothelle DHA PNV Ferrous Fumarate Docusate Folic Acid Vyo Cylate - Pwr Folivane-OB RE Nata OB Thiamine Balanced B50 Complex Escavite Lq Vitamin B1 100 mg Mangadyn One Daily Vitamin and Mineral Dietary Supplement Multi-Nate 30 Right Choice A.M. Multi Formula - Caplet Insur-all Vitamin Supplement RE Prenatal Multivitamin with Iron Tonimol Cap Liq Multiple Vitamins W Minerals Tab Manganese 50mg Plus B1 & E Tab Twin G.F. Powder Integra Plus Vinacal Zeldana Multivitamin with 0.25 mg Fluoride Orti B Total Living Concepts Formula One - Tab Davimet-M Multi-Vitamin Fluoride Livita Children Multiple Vitamins Stress Tab Feminique W Iron and Calcium Tab Multivitamin with 1.0 mg Fluoride Multivitamin with Fluoride Vita-vim With Beta-carotene - Tab Central-vite 18 Essential Multivitamins and Minerals for Men Vitamin B Compound Tab Multiple Vitamins W Iron Tab CitraNatal Rx Beminal W C Fortis Inj Formula Lf Multi Vitamin - Mineral Paramettes Chewable Multivits With Iron Tab Ventrixyl Fe Sopalamine/3b Tab Quflora Pediatric OB Complete Petite Prenate Elite Distilpure Msm PureFe Plus PNV Prenatal Vitamin Plus Vitamin A Prenatabs FA Vitafer - Liq Hi Potency Multi Tab Lipotropic Ctr Super Stress Capsules Penta-thion Pwr Stress B Complex With C, E and Iron Tab Multi-kid Vita-vim - Tab Fortamines 10 Capsules Swical-energy 3e Age P.N. Vitamin-mineral Drink Neonatal DHA Hi Potency B Complex W Chelated Minerals Multiple Vitamins With Iron Tablets Adult Infuvite Multiple Vitamins OB Complete 400 Revit Plus Cap Children's Chewable Multiple Vit.plus Iron Revival 1 Tab Multivitamin Duet DHA 400 ec Mebolic Myhephron Dialysis and Stress Supplement Timed Release Vita-vim Srt Meplex T 750 Vitranol Irospan 24/6 Vitamines Et Mineraux Vitamine Du Groupe B Plus Fer - Liq Chela Potassium Plus OB Complete DHA Extra Once A Day Stress Vitamin B With C Complex Tablets Prenatal Vitamins Plus Pro His Mint Classic Swiss One 10 Multivitamin and Mineral Tab B 50 Capsules C-force Ferra Naka Plus Vitamins Multivitamines Multiple Vitamins and Minerals Tab C.R.T. X Multivitamin & Mineral Powder Mix Prenatal Supplement - Tab PR Natal 430 ec Children's Multivitamins With Iron Vasculine Fibrik Nata Komplete Natural Source Spectrum With Beta Carotene Multi Vitamin and Mineral vitamin Vitamin B1 100mg Tablet B-complex With Vitamin C, Biotin, Folic Acid Formula F L W Vitrexyl plus Iron Foliflex Neonatal Plus Vitamin B50 Complex Children's Chewable With Iron Livita Adults CompleteNate Chewable CitraNatal 90 DHA WestGel DHA Timed Release B-complex 50 Kindervites Viva Kids - Tab Derma-force Multiple Vitamin Tab Elite OB Prenatal Multivitamin One-A-day Advance Fem - Tablets B Virol B 6 Plus Obstetrix EC O-Cal Prenatal Vitamin Neonatal19 Toni Com Liq Men's Biomultiple Vitamin and Mineral Supplement Thiamiject Injection - Liq Im IV 100mg/ml Supravite Stress Avec Vit E Hypo Vites Tab Iron Polysaccharides Folic Acid DHA Vitaphil DHA Mvc Natalvirt 90dha B-complex Tab Se-Natal One WesNate DHA Stress Formula + Iron Vimeral Tab Corvita For-2 Folika-T Glyco Plus Ect Multiple Vit Plus Iron Tab Natalvirt Ca OB Complete Prenatal Beminal Fortis Elx P.R.O. Complex Vitaplex VitaPhil Aide B Complex W C Forte Cap Pediatric Infuvite Multiple Vitamins TriphroCaps For Kids Only Chewable Multivit. Plus Iron Multi-Vitamin Fluoride Drops Multivitamine Stress B With 1000 Mg Vitamin C Cavan Alpha Essential Vitamins and Minerals C. Vit-min Formula Multi Vitamin, Iron and Fluoride MultiVitamin with Fluoride Drops PNV-Select Kanga Sport Vitamins B & C Plus Minerals PureFe OB Plus Cal M Tab B Vitamin Compound With B12 Thunas Rocky Mountain Multiple Vit and Min Mega Tab Prenatal Mega Antioxidant Beminal With C Fortis Cap Tendera-OB High Potency Multivitamins & Minerals Caplets Mega Balance Davimet Multi-Vitamin with Fluoride Supplement De Multivitamines Infusion Arome Fruits Rouges Children Choice Multivit Chewable Tab Virt-Tabs Super Daily No 2 Hemocyte Plus Somavit Brand Vitamins and Minerals Complex WesCap-C-DHA Multi-actin Prenatal Vitamin and Mineral Supplement Tab Infant Multivitamin Drops Multi Vitamins & Minerals Thiamine HCl 100mg W C 20mg Cavan Heme OB Children's Chewable Multivitamins With Minerals Multi Tabs Prenatal Plus Iron Vol-Tab Rx AzesChew DaVITE B-100 Hi Potency B Vitamins Tab Prenatal Plus Stress B&c Tab V & M Vitamin and Mineral Supplement Children's Chewable Multiple Vitamins (chewable Tablets) B-100 Vitamin Supplement CitraNatal DHA MYNEPHROCAPS DIALYSIS/STRESS Vitamin Supplement Twin Ultra Liquid Lemon-lime Flavor Vita-Pac VP-Vite Rx Vasodyn Tab Provida DHA Active OB Concept OB B Plus C 300mg Timed Release Stress B Capsules With Vitamin C Synergistic Manganese Cap Multi Flow Tablets Supravite Bouteille 250ml Multi-vitamins Nutra-Z Multi Plex II - Tab B-1 Caps 500mg Xyzbac G PrePLUS Earthpals Children's Chewables Multi-vitamin & Mineral Tablets Thiamine HCl Injection - Liq 100mg/ml Childrens Chewable Vitamins Children's Vitamins W Iron Chewable Dexivite Poly-Vi-Flor with Iron Efferlife Multivitamins and Minerals Floriva Plus Paramettes Syrup Prenatal Plus Vitamins TRONVite Vtb Vitamin and Mineral Supplement Balanced B100 Vitramyn Niva-Plus Vitamin B Complex W C 300mg Tab Fortamines-10 Comprimes Livron Plus Tab Keylosa Spectrum Performa Multivitamins and Minerals Tablets Folic-K Dalivit Marnatal F B Plus C 300 mg Corvite Free Formula Hh Leritone Junior Vitamines Pour Bebes Et Enfants Osteo-force Lysamine Diet Supp Amp-tab Multi-phyto Capsules Prenatal Formula Tab Kid's Choice Children's Chewable Vitamins - Tab Genicin Vita-Q Formula Fm Vitamins & Minerals Tab B-100 Complex Tablets Multi - N.T.O.x Formula - Tab Pregvit Folic 5 Super Pantoplex Abavite Time Release B 100 Compound - Tablet Glyco-aide Tab Complete Multivitamins and Minerals Tablets Timed Release Pnv-OB-dha Flintstones W Extra C Tab NESTABS Prenatal Multi-vitamin/Mineral Supplement Quflora FE Pediatric Drops Vit B Complex Plus Vit C 550mg Prometa Folika-NC B C Antistress Cap Omnivex Super Vita Vim Multivitamins and Minerals B-50 Hi Potency B Vitamins Tab Q.T. #4 Vitamin and Mineral Dietary Supplement NataFort PROTECT IRON Liquid vitaMedMD One Rx Wellness Formula Maxi 6 Liq Gynedyn Tab Vitamin B + C Cap Childrens Chewable Multivitamins Vita-worth B-complex Tablets Vena-Bal DHA Obstetrix DHA Combo Pack B Complex W Vit C W Non-med Yeast&liver Tab Thiamine HCl Inj 100mg/ml Harvest Of Values All B Complex Tab Liqui B Complex Plus Balanced B 125 Srt Pregvit Folic 4 Everyday Multiple Vitamins With Iron Surbex-500 With Iron Liqui Infant Vitamins Neo Bex Elixir Strovite One Caplets Livron Plus Ampoule PR Natal 400 ec Multi Vitamin Drops with Fluoride with Iron Prenatal Vitamins and Minerals Tablets vitaMedMD Rx Plus Vol-Nate Stress Tab With Zinc, Copper and Vitamin E Vitamin B Complex Plus 300mg Vitamin C Spark Cap NephPlex Rx Multi-Vitamin Fluoride and Iron Drops Venexa Multi Vite Liq Junior NESTABS ABC Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA Se-Plete DHA Croq-vit Pour Enfants Vital Be-100 Centratex PreNatal 19 Opti-manganese + B1 + C Caplet Ultra Hr Q.T. Vitamin and Mineral Drink Mix Zyvit Nrg Plus Liq D'pantothenic Acid-B1-B2 Tab Hemarexin Tab B1 400mg Ctr Tab Multivitamins for Children Phytofortis + Calcium A-D Hyporyl - Tab Vitafol Plus Junior Multi Vitamins - Regular Century Complete Children's Chewable Vit and Min Tab Onccor Chewable Children's Complete Multivitamins With Essential Minerals Tandem Plus Thrivite 19 Timed Release B Complex 100 Srt DuetDHA Balanced B-100 Caps Enviroflex - Tab Childrens Chewable Multivitamins W Iron DuetDHA Complete healthy mamaBE WELL ROUNDED BE WELL ROUNDED Chewable Adult Multivitamins With Minerals Multi Nt-OX Numark Multivitamins B-complex Tablets Childrens Chewable Multiple Vitamins Tab Vitamin B Complex Tab Davimet with Fluoride Maintain Multiple Vitamin & Minerals Multivitamines Et Mineraux Junior Regulier One-A-day Advance Men's Vigo Multivitamins Drops/lozenge Gesticare DHA Stress Complex 600 Avec Vit E Cuivre Zinc B6 Plus Tab Multivitamins and Minerals With Betacarotene Tablets Hill.vite Vitafol Ultra THIAMINE HCl Vita Vim With Beta Carotene-caplet Men's Multi Master Formula Vit B1 Ctr Srt 100mg Trinatal Rx 1 Vita Vim Multivitamins and Minerals Tab Extra P.N. Vitamin-mineral Drink Mix Envirocomplex Children's Chewable Multi Vit W Iron Methaver PM Caps Vita-B Chewable Multivitamins Multi-Vitamin With Fluoride Foltabs Prenatal Poly-Vitamin with Fluoride Kanga-kid Multi-vitamin & Mineral Pretrate Materna Vita B Complex Tab Sopalamine 3b Plus Maxine Vitamin and Mineral Supplement Sopalamine/3b Plus C Original Bioscal Forte Multi-vitamin Supplement Capsules Vita Day Tab Multi-Vitamin Drops with Fluoride and Iron Genicin Vita-S Megavite Rx Vitaday Junior Tab Vitafol One Complete One A Day Tab B Complex Plus C 300mg Tab Acti-MN + B1 + C Caplet Vitamin B1 Tab 100mg Bewon Elixir Women's Biomultiple Vitamin and Mineral Supplement Poly-Vite Pediatric Oral Solution Omniquin One Per Day Vitamin and Mineral Dietary Supplement Body Rox Thrivite Rx Ventrixyl Neo-vites & Minerals Tab TM-Vite RX MultiVitamin Drops with Fluoride and Iron Multiple Vitamins With Iron RenaPlex-D Supravite Pour Enfants B-Combo One A Day Advance Adults Relnate DHA Synergistic Manganese Capsules Vitamin B Compound W Vit C 250mg Tab Twin Ultra Liquid Fruit Punch Flavor Adeks - Dps Childrens Chewable Vitamins W Iron NovaMV Multivitamin Se-Care Conceive Surbex 500 Filmtab Daily-Vite Chromease Tab High Potency Vitamin B Complex + C Tab Supravite Stress Avec Vit E Et Fer Prenatrix Children's Chewable Multi Vitamins Florafol Pediatric 0.25 mg/mL Multivitamin and Fluoride Liquid Drops Novel Vita B Totum 500 Tricare Prenatal Compleat Alkadrenergy Tablets Children's Vitamins Chewable Multivitamines Et Mineraux Reguliers / Regular Multivitamins and Minerals Twin Opti Pwr Paramettes Chewable Multivitamins Plus Iron Multi Vitamin Drops with Fluoride and Iron V-Natal E.S.T. Complex C-Nate DHA Vitafant 24 Multivitamins + Minerals Quflora FE Phytoplex B Liq Stress B Complex With C and E Tab Vitrexate Great Day/am Formula Tab Vitamin B Compound W C Tab 500mg Multivitamins and Multiminerals Formula Regular Tablet Sun-rype Vitaburst 50 Plus Prena1 Betaxin Liq 100mg/ml T.R.I. B-plex Src Infuvite Adult Multiple Vitamins PNV Prenatal Vitamin PR Natal 400 Multi 12 Injection B-complex Vitamines Et Mineraux Comprimes CitraNatal Essence Childrens Chewab Vitamin W Chel Minerals Beminal 500 Tab Adeks Tablets Mega-vim 75 With Beta-carotene - Tablets Lorid NESTABS DHA Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA Prim - Royal P.M.T. OBTREX DHA Combo Pack Focalgin CA FolaMed DHA Poly-Vi-Flor Amladex Swiss One Multivitamin and Mineral Caplet Kanga-B Vitamin B Group + C Taron-C DHA Prenatal Vi-min Thiamine HCl Tab 25mg Formula Pro-B Vitamin B Complex W C Tab Cda-21 Vitamins With Non-medicinal Probiotic Complex One A Day Tab Multivit with Fluoride Cedevita Sugar-free Vitamin Supplement Pnv Ob DHA Tricare Prenatal Quick Dissolve PreferaOB plus DHA Escavite D One A Day Multiple Vit W Minerals Surbex-500 With Zinc Children's Chewable Multiple Vitamins - Tab M-Natal Plus Vitamin and Mineral Supplement - Liq Poly-VI-sol Drops Vitamin B Complex + C 600mg Tab Antlerviron Complete One-A-day - Tab Vit B Complex Ctr Kimchi Vitamin chewable multivitamin Hormodausse Plus Calc Et D Tab Pnv-VP-U Multi 1000 Dr. AVi MULTIVITAMIN with Zinc, Real Ginger, Lemon and Lemongrass Dexifol MultiVitamin with Fluoride Chewable Vitranol Fe Azesco Fortaplex Inj Zoo Chews Flintstones Multiple Vitamins Multi-11 Pro Hers Vanilla Revitalize Multi-vitamin and Mineral Complex Folika-V For Kids Only Chewable Multivitamins Hemarexin Liquid and Drinkable Ampoules Iron, Vit & Min Supp TL-Care DHA O-Cal FA multivitamin Hemarexin Amp Vitamin B1 Tablets 100mg H.W. Children's Chewable Multi Vit & Mineral PNV-First Swical-energy-2 Prenatal Vitamin and Mineral Supplement -tab Childrens Chew Multi Vitamin Tab Tricare Prenatal 2-part Daily Prenatal Vitamin System Trinatal Ultra Pediatric Infuvite Multiple Vitamins for Infusion Nutra Boost Se-Natal Diaplex Prenatvite Complete Children's Chewable Multiple Vitamins With Extra Vitamin C (chewable Tablets) Ultimate Tab Vitogen B Stress C Vit E Zinc & Cop Kenwood Liquid Supplement Replavite TL-Folate Nutri-Tab OB Stress Tab With Iron and Vitamin E Poly-Vi-Sol Zatean-Pn Grand Master Formula Tab Multivitamin with fluoride Acti-thiamine Caplet 100mg One Daily VITES One Tablet Daily Mens Formula Vitamin B1 Tab 100mg USP M.V.I. Pediatric Nephrocaps Balanced B-50 B-complex Vitamins, Timed Rele Vitamine 110 Liq Nutri-Tab OB plus DHA RE FAC-x Zintrexyl-C Dexatran Super Kids Chewable Multivitamin Multimineral (chewable Tablets) Multivitamin & Multimineral Glyco Lite Ect Bugs Bunny Chew Multi Vit Plus Iron Vitamin B-1 100 Mg Tablets Mega Plex IV - Pck Multiple Vitamins Plus Iron for Women MultiVitamin, Iron and Fluoride Drops NovaFerrum Multivitamin with Iron Pediatric Drops Ply Vi Sol Chewable Tab Dexatrim Tablets Prevital Tab Vitamin B Complex 50 Garfield Chewable Multivitamins Tab Active FE B-50 Complex Tab Multiple Vitamins Plus Iron Tab N.E.U. Complex Vinate AZ Children's Chewable Multiple Vitamins With Iron Tablets (chewable Tablets) B-plex 100 Adult Formula 50+ Infantol Drops Nutrifer Plus Tablets Card-floe II Tab Complex 5 - Pwr Thiamine HCl Tab 50mg Vitafol Caplet Vitamin B Complex Multitabs Essential B Tablets Allbee C 800 Tab M.V.I.-12 Virt-C DHA Multiple Vitamins Tab Nutra-clear Bev B-150 Se-Tan PLUS Florafol FE Pediatric 0.25 mg/mL Multivitamin and Fluoride Liquid Drops Tricare Prenatal DHA One With Folate Alsimine W Vitamins A D Chewable Multiple Vit Plus Iron for Children B-plex Tender Age Multi Vitamins Renal Caps Dialysis/Stress Vitamin Supplement SetonET-EC Avon Vitadvance Multi-kids Complete Select OB Balanced B-100 Timed Release Multivitamins and Minerals Tablets Multi Spectrum - Tablet Supravite Stress Avec Vit E Cuivre Et Zinc TL-Fluorivite Multi-Vit with Fluoride Complete Multivitamins and Minerals for Children Super Stress Mega B Plus 1000mg Vit C Tab Virt Nate Multivitamins and Minerals for Young Women Prenatal Vitamin and Mineral Supplement Complexe B Compose 75 Milltrium Senior Vitamin and Mineral Supplement Vitaday Tab Natal PNV 50 Plus Multiple Vitamins & Minerals Renate Stress B Complex With C, E & Iron Vita-B-75 Cap bioJET Chew.multiple Vits.with Extra C for Children Multivitamins and Minerals - Complete Vit-HA Multi Vitamin and Zinc Supplement Cavan-EC SOD DHA Vita Plex Tab Moms Choice Rx Bewon Elixir 0.05mg/ml Cedevita Plus Vitamin Supplement Viamon Ampoules Et Comprimes Neo-bex NEONATAL Complete Poly-VI-flor Iron 25mg With Vit B-cmplx, Vit C, Cu & Mo Stress B-complex Plus Iron With Vitamins C&e Maltlevol Liq B Complex 25mg Vitamin Supplement Childrens Chewable Vitamin Tab Multivitamins Floriva Thiamine Hydrochloride Injection, USP Bacmin Appedrine M.V.I. 12 Betaxin Multivitamin Drops with Fluoride Paramettes Adults Revit Multi-vitamins and Minerals Bev 29 Tab Fusion Plus Tricare Prenatal Alertonic Zalvit B-50 Complex Natavite Chewable Multiple Vitamins Plus Iron Tab Vitamin B Complex Suppl Vitamin B Complex + C 300mg Cap Vitazyme Reno Caps Am Caps Multi-vitamin Dietary Supplement B Complex With C 550mg For Kids Only Chewable Multivitamins - Tab Liqui B Complex Mini-B Tab Virt-Pn Complete Natal DHA
Indication	For the treatment of thiamine and niacin deficiency states, Korsakov's alcoholic psychosis, Wernicke-Korsakov syndrome, delirium, and peripheral neuritis.
Categories	Alimentary Tract and Metabolism Diet, Food, and Nutrition Food Growth Substances Micronutrients OCT1 substrates OCT2 Inhibitors Physiological Phenomena Pyrimidines Sulfur Compounds Thiazoles Vitamin B Complex Vitamins
ATC-Code	A11DA01
CAS number	70-16-6

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Thiamin pyrophosphokinase 1	MEHAFTPLEPLLSTGNLKYCLVILNQPLDNYFRHLWNKALLRACADGGAN...	unknown	substrate
Cytochrome P450 4B1	MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRQTLAKAMDKFPGPP...	unknown	inducer
Thiamin pyrophosphokinase 1	MEHAFTPLEPLLSTGNLKYCLVILNQPLDNYFRHLWNKALLRACADGGAN...	unknown	substrate
Ectonucleoside triphosphate diphosphohydrolase 5	MATSWGTVFFMLVVSCVCSAVSHRNQQTWFEGIFLSSMCPINVSASTLYG...	unknown	substrate
Thiamine-triphosphatase	MAQGLIEVERKFLPGPGTEERLQELGGTLEYRVTFRDTYYDTPELSLMQA...	unknown	substrate
Serum albumin	MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIA...	unknown	binder
Solute carrier family 22 member 2	MPTTVDDVLEHGGEFHFFQKQMFFLLALLSATFAPIYVGIVFLGFTPDHR...	unknown	inhibitor
Solute carrier family 22 member 1	MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHC...	unknown	substrate
Solute carrier family 22 member 5	MRDYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFTGLSSVFLIATPEHRC...	unknown	inhibitor
Thiamine transporter 1	MDVPGPVSRRAAAAAATVLLRTARVRRECWFLPTALLCAYGFFASLRPSE...	unknown	substrate
Thiamine transporter 2	MDCYRTSLSSSWIYPTVILCLFGFFSMMRPSEPFLIPYLSGPDKNLTSAE...	unknown	substrate
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Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682